mTOR as a central regulator of lifespan and aging [version 1; peer review: 3 approved]
The mammalian/mechanistic target of rapamycin (mTOR) is a key component of cellular metabolism that integrates nutrient sensing with cellular processes that fuel cell growth and proliferation. Although the involvement of the mTOR pathway in regulating life span and aging has been studied extensively...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2019-07-01
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Series: | F1000Research |
Online Access: | https://f1000research.com/articles/8-998/v1 |