| Summary: | Sebaceous carcinoma (SebCa), is the second most frequent malignancy of the eyelid. It often presents with non-specific clinical features and is known for mimicking benign inflammatory lesions such as chalazion. The masquerading ability of this highly invasive neoplasm can delay or mislead the diagnosis, resulting in significant morbidity and mortality. Here, we report a rare case of a 91-year-old man presenting with a lesion clinically apparent to a chalazion with a histopathologically proven diagnosis of SebCa adjacent to a chalazion. This report highlights the presentation of sebaceous carcinoma masquerade syndrome and supports a thorough histopathological examination of all surgically excised chalazions.
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