Enhancer-associated long non-coding RNA LEENE regulates endothelial nitric oxide synthase and endothelial function
eNOS expression is dynamically regulated both transcriptionally and post-transcriptionally by various stimuli. Here the authors identify an enhancer-associated lncRNA (LEENE) that is co-regulated with, and enhances eNOS expression.
Main Authors: | Yifei Miao, Nassim E. Ajami, Tse-Shun Huang, Feng-Mao Lin, Chih-Hong Lou, Yun-Ting Wang, Shuai Li, Jian Kang, Hannah Munkacsi, Mano R. Maurya, Shakti Gupta, Shu Chien, Shankar Subramaniam, Zhen Chen |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-017-02113-y |
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