Effects of Diet Induced Weight Reduction on Cartilage Pathology and Inflammatory Mediators in the Joint Tissues

Effects of Diet Induced Weight Reduction on Cartilage Pathology and Inflammatory Mediators in the Joint Tissues

Obesogenic diets contribute to the pathology of osteoarthritis (OA) by altering systemic and local metabolic inflammation. Yet, it remains unclear how quickly and reproducibly the body responds to weight loss strategies and improve OA. In this study we tested whether switching obese diet to a normal...

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Bibliographic Details
Main Authors: Antonia RuJia Sun, Xiaoxin Wu, Ross Crawford, Hongxing Li, Lin Mei, Yong Luo, Yin Xiao, Xinzhan Mao, Indira Prasadam
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Medicine
Subjects:
osteoarthritis
diet induced obesity
infrapatellar fat pad
synovium
inflammation
cartilage
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.628843/full

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