PTEN at the crossroad of metabolic diseases and cancer in the liver
The tumor suppressor PTEN is a phosphoinositide phosphatase regulating the PI3K/Akt signaling pathways and mutated or deleted in a variety of human cancers. Recent evidence indicates that dysregulated PTEN expression and activity in the liver critically affect hepatic insulin sensitivity and trigger...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2008-07-01
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| Series: | Annals of Hepatology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1665268119318484 |