Simulations on Simple Models of Connexin Hemichannels Indicate That Ca<sup>2+</sup> Blocking Is Not a Pure Electrostatic Effect

Simulations on Simple Models of Connexin Hemichannels Indicate That Ca<sup>2+</sup> Blocking Is Not a Pure Electrostatic Effect

Connexin hemichannels allow the unspecific but regulated interchange of molecules from ions to second messenger and ATP, between the eukariotic cell and its extracellular space. The transport of ions and water through hemichannels is important for physiological functions and also in the progression...

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Bibliographic Details
Main Authors: Felipe Villanelo, Jorge Carrasco, Joaquin Jensen-Flores, Jose Antonio Garate, Tomas Perez-Acle
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Membranes
Subjects:
connexin
hemichannel
calcium-binding
simulation
Online Access:https://www.mdpi.com/2077-0375/11/5/372

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