Drosophila neprilysins control insulin signaling and food intake via cleavage of regulatory peptides

Drosophila neprilysins control insulin signaling and food intake via cleavage of regulatory peptides

Insulin and IGF signaling are critical to numerous developmental and physiological processes, with perturbations being pathognomonic of various diseases, including diabetes. Although the functional roles of the respective signaling pathways have been extensively studied, the control of insulin produ...

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Bibliographic Details
Main Authors: Benjamin Hallier, Ronja Schiemann, Eva Cordes, Jessica Vitos-Faleato, Stefan Walter, Jürgen J Heinisch, Anders Malmendal, Achim Paululat, Heiko Meyer
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-12-01
Series:eLife
Subjects:
insulin signaling
insulin expression
feeding behavior
peptide metabolism
metallopeptidase
neprilysin
Online Access:https://elifesciences.org/articles/19430

Internet

https://elifesciences.org/articles/19430

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