Tuberculous Meningitis Presenting with Sudden Deterioration and Demise after Ceftriaxone Withdrawal: A Case Report and Review of Literature

Tuberculous Meningitis Presenting with Sudden Deterioration and Demise after Ceftriaxone Withdrawal: A Case Report and Review of Literature

Tuberculous Meningitis (TBM) is a challenging condition to diagnose due to its non-specific clinical presentation and the limited sensitivity of existing laboratory techniques. Here we report an unusual presentation of TBM in a Nigerian teenager who presented with fever, headache, neck stiffness and...

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Bibliographic Details
Main Authors: Francis Ikechukwu Ukekwe, Ann Ebele Aronu, Isaiah Ogbonna Nwidenyi, Ngozi Chinyelu Ojinnaka
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2019-09-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
autopsy
diagnosis
tuberculosis
Online Access:https://jcdr.net/articles/PDF/13165/42345_CE[Ra1]_F(KM)_PF1(AG_SHU)_PFA(KM)_PB(AG_KM)_PN(SL).pdf
Description
Summary:Tuberculous Meningitis (TBM) is a challenging condition to diagnose due to its non-specific clinical presentation and the limited sensitivity of existing laboratory techniques. Here we report an unusual presentation of TBM in a Nigerian teenager who presented with fever, headache, neck stiffness and progressive weight loss, and who had remarkable improvement while on ceftriaxone but had sudden deterioration and demise on withdrawal of ceftriaxone. Postmortem findings of TBM underlie the need for a high index of suspicion to enable early diagnosis, proper treatment and better prognosis.
ISSN:2249-782X
0973-709X

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