Nerve growth factor promotes survival of new neurons in the adult hippocampus

Exogenously provided NGF enhances cognitive performance in impaired rodents and humans and is currently a promising compound for the treatment of dementia. To investigate whether NGF-dependent cognitive improvement may be due in part to increased hippocampal neurogenesis, adult and aged male rats we...

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Bibliographic Details
Main Authors: Helena Frielingsdorf, Daniel R. Simpson, Leon J. Thal, Donald P. Pizzo
Format: Article
Language:English
Published: Elsevier 2007-04-01
Series:Neurobiology of Disease
Subjects:
NGF
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106003081