A Case of Metastatic Urachal Carcinoma Treated With FOLFIRI (irinotecan and 5-Fluorouracil/leucovorin) Plus Bevacizumab

A Case of Metastatic Urachal Carcinoma Treated With FOLFIRI (irinotecan and 5-Fluorouracil/leucovorin) Plus Bevacizumab

A 68-year-old man was introduced to our hospital for the treatment of lung and mediastinum lymph node metastases that originated from an urachal carcinoma 4 years after a partial cystectomy. First-line chemotherapy with an S-1 and cisplatin combination was ineffective. The patient received FOLFIRI p...

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Bibliographic Details
Main Authors: Tomohiro Kanamaru, Taro Iguchi, Nao Yukimatsu, Yasuomi Shimizu, Yuki Kohyama, Hirokazu Tachibana, Minoru Kato, Takeshi Yamasaki, Satoshi Tamada, Tatsuya Nakatani
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:Urology Case Reports
Subjects:
Urachal carcinoma
Chemotherapy
FOLFIRI
Bevacizumab
Online Access:http://www.sciencedirect.com/science/article/pii/S2214442014001466
Description
Summary:A 68-year-old man was introduced to our hospital for the treatment of lung and mediastinum lymph node metastases that originated from an urachal carcinoma 4 years after a partial cystectomy. First-line chemotherapy with an S-1 and cisplatin combination was ineffective. The patient received FOLFIRI plus bevacizumab chemotherapy as salvage chemotherapy. Stability was achieved after eight cycles of FOLFIRI plus bevacizumab therapy. We conducted a biopsy of the metastatic tumor, and the pathology of the biopsy tissue was partially necrotic. To our knowledge, this case represents the first report of a metastatic urachal carcinoma treated with FOLFIRI plus bevacizumab.
ISSN:2214-4420

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