Fiber-specific white matter alterations in early-stage tremor-dominant Parkinson’s disease

Abstract Using a fixel-based analysis (FBA), we assessed the fiber-specific white matter (WM) alterations in nonmedicated patients with early-stage Parkinson’s disease (PD) with tremor-dominant (TD; n = 53; mean age, 61.7 ± 8.7 years) and postural instability and gait disorder (PIGD; n = 27; mean ag...

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Bibliographic Details
Main Authors: Christina Andica, Koji Kamagata, Yuya Saito, Wataru Uchida, Shohei Fujita, Akifumi Hagiwara, Toshiaki Akashi, Akihiko Wada, Takashi Ogawa, Taku Hatano, Nobutaka Hattori, Shigeki Aoki
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-021-00197-4