Design, Synthesis and Antiviral Activity Studies of Schizonepetin Derivatives

Design, Synthesis and Antiviral Activity Studies of Schizonepetin Derivatives

A series of schizonepetin derivatives have been designed and synthesized in order to obtain potent antivirus agents. The antiviral activity against HSV-1 and influenza virus H3N2 as well as the cytotoxicity of these derivatives was evaluated by using cytopathic effect (CPE) inhibition assay in vitro...

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Bibliographic Details
Main Authors: Anwei Ding, Mingqiu Shan, Weifeng Yao, Yudan Cao, Li Zhang, Zhengjie Meng, Beihua Bao, Zheng Meng, Nianguang Li
Format: Article
Language:English
Published: MDPI AG 2013-08-01
Series:International Journal of Molecular Sciences
Subjects:
chizonepetin
anti-virus activity
HSV-1
H3N2
Online Access:http://www.mdpi.com/1422-0067/14/8/17193

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