Validation of a new classifier for the automated analysis of the human epidermal growth factor receptor 2 (HER2) gene amplification in breast cancer specimens

Validation of a new classifier for the automated analysis of the human epidermal growth factor receptor 2 (HER2) gene amplification in breast cancer specimens

<p>Abstract</p> <p>Amplification of the human epidermal growth factor receptor 2 (HER2) is a prognostic marker for poor clinical outcome and a predictive marker for therapeutic response to targeted therapies in breast cancer patients. With the introduction of anti-HER2 therapies, a...

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Bibliographic Details
Main Authors: Furrer Daniela, Jacob Simon, Caron Chantal, Sanschagrin François, Provencher Louise, Diorio Caroline
Format: Article
Language:English
Published: BMC 2013-02-01
Series:Diagnostic Pathology
Subjects:
Fluorescence <it>in situ</it> hybridization (FISH)
Trastuzumab
HER2
Image analysis
Tile-sampling analysis
Nuclei-sampling analysis
Nuclei analysis
Accuracy
Breast cancer
Online Access:http://www.diagnosticpathology.org/content/8/1/17

Internet

http://www.diagnosticpathology.org/content/8/1/17

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