Spatiotemporal regulation of Aurora B recruitment ensures release of cohesion during C. elegans oocyte meiosis

During meiosis, step-wise release of sister chromatid cohesion mediated by REC-8 cohesin is required for the formation of haploid gametes. Here, the authors show that in C. elegans oocytes, regulated recruitment of Aurora B kinase ensures the correct distribution of REC-8 phosphorylation, which prom...

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Main Authors:	Nuria Ferrandiz, Consuelo Barroso, Oana Telecan, Nan Shao, Hyun-Min Kim, Sarah Testori, Peter Faull, Pedro Cutillas, Ambrosius P. Snijders, Monica P. Colaiácovo, Enrique Martinez-Perez
Format:	Article
Language:	English
Published:	Nature Publishing Group 2018-02-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-018-03229-5

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spelling	doaj-a5f72f87d8f44fc2a699bfa24b78e92b2021-05-11T09:20:47ZengNature Publishing GroupNature Communications2041-17232018-02-019111610.1038/s41467-018-03229-5Spatiotemporal regulation of Aurora B recruitment ensures release of cohesion during C. elegans oocyte meiosisNuria Ferrandiz0Consuelo Barroso1Oana Telecan2Nan Shao3Hyun-Min Kim4Sarah Testori5Peter Faull6Pedro Cutillas7Ambrosius P. Snijders8Monica P. Colaiácovo9Enrique Martinez-Perez10MRC London Institute of Medical Sciences, Imperial College LondonMRC London Institute of Medical Sciences, Imperial College LondonMRC London Institute of Medical Sciences, Imperial College LondonMRC London Institute of Medical Sciences, Imperial College LondonDepartment of Genetics, Harvard Medical SchoolMRC London Institute of Medical Sciences, Imperial College LondonMRC London Institute of Medical Sciences, Imperial College LondonMRC London Institute of Medical Sciences, Imperial College LondonMRC London Institute of Medical Sciences, Imperial College LondonDepartment of Genetics, Harvard Medical SchoolMRC London Institute of Medical Sciences, Imperial College LondonDuring meiosis, step-wise release of sister chromatid cohesion mediated by REC-8 cohesin is required for the formation of haploid gametes. Here, the authors show that in C. elegans oocytes, regulated recruitment of Aurora B kinase ensures the correct distribution of REC-8 phosphorylation, which promotes cohesion release.https://doi.org/10.1038/s41467-018-03229-5
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Nuria Ferrandiz Consuelo Barroso Oana Telecan Nan Shao Hyun-Min Kim Sarah Testori Peter Faull Pedro Cutillas Ambrosius P. Snijders Monica P. Colaiácovo Enrique Martinez-Perez
spellingShingle	Nuria Ferrandiz Consuelo Barroso Oana Telecan Nan Shao Hyun-Min Kim Sarah Testori Peter Faull Pedro Cutillas Ambrosius P. Snijders Monica P. Colaiácovo Enrique Martinez-Perez Spatiotemporal regulation of Aurora B recruitment ensures release of cohesion during C. elegans oocyte meiosis Nature Communications
author_facet	Nuria Ferrandiz Consuelo Barroso Oana Telecan Nan Shao Hyun-Min Kim Sarah Testori Peter Faull Pedro Cutillas Ambrosius P. Snijders Monica P. Colaiácovo Enrique Martinez-Perez
author_sort	Nuria Ferrandiz
title	Spatiotemporal regulation of Aurora B recruitment ensures release of cohesion during C. elegans oocyte meiosis
title_short	Spatiotemporal regulation of Aurora B recruitment ensures release of cohesion during C. elegans oocyte meiosis
title_full	Spatiotemporal regulation of Aurora B recruitment ensures release of cohesion during C. elegans oocyte meiosis
title_fullStr	Spatiotemporal regulation of Aurora B recruitment ensures release of cohesion during C. elegans oocyte meiosis
title_full_unstemmed	Spatiotemporal regulation of Aurora B recruitment ensures release of cohesion during C. elegans oocyte meiosis
title_sort	spatiotemporal regulation of aurora b recruitment ensures release of cohesion during c. elegans oocyte meiosis
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2018-02-01
description	During meiosis, step-wise release of sister chromatid cohesion mediated by REC-8 cohesin is required for the formation of haploid gametes. Here, the authors show that in C. elegans oocytes, regulated recruitment of Aurora B kinase ensures the correct distribution of REC-8 phosphorylation, which promotes cohesion release.
url	https://doi.org/10.1038/s41467-018-03229-5
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Spatiotemporal regulation of Aurora B recruitment ensures release of cohesion during C. elegans oocyte meiosis

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