Development of a Novel Metagenomic Biomarker for Prediction of Upper Gastrointestinal Tract Involvement in Patients With Crohn’s Disease

Development of a Novel Metagenomic Biomarker for Prediction of Upper Gastrointestinal Tract Involvement in Patients With Crohn’s Disease

The human gut microbiota is an important component in the pathogenesis of Crohn’s disease (CD), promoting host–microbe imbalances and disturbing intestinal and immune homeostasis. We aimed to assess the potential clinical usefulness of the colonic tissue microbiome for obtaining biomarkers for upper...

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Bibliographic Details
Main Authors: Min Seob Kwak, Jae Myung Cha, Hyun Phil Shin, Jung Won Jeon, Jin Young Yoon
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Microbiology
Subjects:
microbiome
16S rRNA
Crohn’s disease
upper gastrointestinal tract
biomarker
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01162/full

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