The Potential Role of Coagulation Factor Xa in the Pathophysiology of COVID-19: A Role for Anticoagulants as Multimodal Therapeutic Agents
SARS-CoV-2 infection (COVID-19) results in local and systemic activation of inflammation and coagulation. In this review article, we will discuss the potential role of coagulation factor Xa (FXa) in the pathophysiology of COVID-19. FXa, a serine protease, has been shown to play a role in the cleavag...
Main Authors: | Galit H. Frydman, Michael B. Streiff, Jean M. Connors, Gregory Piazza |
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Format: | Article |
Language: | English |
Published: |
Georg Thieme Verlag KG
2020-10-01
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Series: | TH Open |
Subjects: | |
Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1718415 |
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