Identification of Ser465 as a novel PINK1 autophosphorylation site

Identification of Ser465 as a novel PINK1 autophosphorylation site

Abstract Background PINK1 (PTEN-induced putative kinase 1) gene is the causal gene for recessive familial type 6 of Parkinson’s disease (PARK6), which is an early-onset autosomal recessive inherited neurodegenerative disease. PINK1 has been reported to exert both autophosphorylation and phosphorylat...

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Bibliographic Details
Main Authors: Ji-feng Guo, Ling-yan Yao, Qi-ying Sun, Yi-ting Cui, Yang Yang, Qian Xu, Xin-xiang Yan, Bei-sha Tang
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Translational Neurodegeneration
Subjects:
Parkinson’s disease
PINK1
Autophosphorylation sites
Kinase activity
Online Access:http://link.springer.com/article/10.1186/s40035-017-0103-7

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http://link.springer.com/article/10.1186/s40035-017-0103-7

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