Pathogenesis of Cognitive Dysfunction in Patients with Obstructive Sleep Apnea: A Hypothesis with Emphasis on the Nucleus Tractus Solitarius
OSA is characterized by the quintessential triad of intermittent apnea, hypoxia, and hypoxemia due to pharyngeal collapse. This paper highlights the upstream mechanisms that may trigger cognitive decline in OSA. Three interrelated steps underpin cognitive dysfunction in OSA patients. First, several...
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| Format: | Article |
| Language: | English |
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Hindawi Limited
2012-01-01
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| Series: | Sleep Disorders |
| Online Access: | http://dx.doi.org/10.1155/2012/251096 |