Novel roles of the multifunctional CCR4-NOT complex in post-transcriptional regulation

The CCR4-NOT complex is highly conserved gene silencer, and more general functions of the complex have been elucidated at post-transcriptional levels. Specific regulatory proteins, including miRNA-induced silencing complex and its associate protein, bind to 3’-UTR elements and recruit the CCR4-NOT c...

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Bibliographic Details
Main Authors: Toshifumi eInada, Shiho eMakino
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00135/full