Generating biomembrane-like local curvature in polymersomes via dynamic polymer insertion

Investigating biomembrane curvature formation is important for studying intracellular processes, but the instability of liposome models mimicking these membranes restricts exploration of membrane processes. Here, the authors demonstrate control over the curvature formation in polymersome membranes b...

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Bibliographic Details
Main Authors: Jiawei Sun, Sjoerd J. Rijpkema, Jiabin Luan, Shaohua Zhang, Daniela A. Wilson
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22563-9
Description
Summary:Investigating biomembrane curvature formation is important for studying intracellular processes, but the instability of liposome models mimicking these membranes restricts exploration of membrane processes. Here, the authors demonstrate control over the curvature formation in polymersome membranes by insertion of PNIPAm as stimuli responsive polymer.
ISSN:2041-1723