Progress of dorsal root ganglia in mechanism of pain

Dorsal root ganglia (DRG) neurons are the primary afferent neurons of algaesthesis of trunk and extremities. DRG transmits and accommodates sensations and accepts and conveys nociception, so it plays an important role in the mechanism of pain. DRG is accessible to clinical interventions for the cont...

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Main Author: Jing-zhi LIU
Format: Article
Language:English
Published: Tianjin Huanhu Hospital 2018-10-01
Series:Chinese Journal of Contemporary Neurology and Neurosurgery
Subjects:
Online Access:http://www.cjcnn.org/index.php/cjcnn/article/view/1846
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spelling doaj-a5ccc5b74c6647f288f808a84156114a2020-11-25T02:42:01ZengTianjin Huanhu HospitalChinese Journal of Contemporary Neurology and Neurosurgery1672-67312018-10-01181070570810.3969/j.issn.1672-6731.2018.10.0021801Progress of dorsal root ganglia in mechanism of painJing-zhi LIU0Pain Management Center, the Second Hospital of Tianjin Medical University, Tianjin 300211, ChinaDorsal root ganglia (DRG) neurons are the primary afferent neurons of algaesthesis of trunk and extremities. DRG transmits and accommodates sensations and accepts and conveys nociception, so it plays an important role in the mechanism of pain. DRG is accessible to clinical interventions for the control of intractable pain and is a target for neuromodulation therapy. This review focuses on sodium ion channels in DRG, glial cells and inflammatory reaction which are mainly involved in the mechanism of pain. DOI: 10.3969/j.issn.1672-6731.2018.10.002http://www.cjcnn.org/index.php/cjcnn/article/view/1846Ganglia, spinalPainReview
collection DOAJ
language English
format Article
sources DOAJ
author Jing-zhi LIU
spellingShingle Jing-zhi LIU
Progress of dorsal root ganglia in mechanism of pain
Chinese Journal of Contemporary Neurology and Neurosurgery
Ganglia, spinal
Pain
Review
author_facet Jing-zhi LIU
author_sort Jing-zhi LIU
title Progress of dorsal root ganglia in mechanism of pain
title_short Progress of dorsal root ganglia in mechanism of pain
title_full Progress of dorsal root ganglia in mechanism of pain
title_fullStr Progress of dorsal root ganglia in mechanism of pain
title_full_unstemmed Progress of dorsal root ganglia in mechanism of pain
title_sort progress of dorsal root ganglia in mechanism of pain
publisher Tianjin Huanhu Hospital
series Chinese Journal of Contemporary Neurology and Neurosurgery
issn 1672-6731
publishDate 2018-10-01
description Dorsal root ganglia (DRG) neurons are the primary afferent neurons of algaesthesis of trunk and extremities. DRG transmits and accommodates sensations and accepts and conveys nociception, so it plays an important role in the mechanism of pain. DRG is accessible to clinical interventions for the control of intractable pain and is a target for neuromodulation therapy. This review focuses on sodium ion channels in DRG, glial cells and inflammatory reaction which are mainly involved in the mechanism of pain. DOI: 10.3969/j.issn.1672-6731.2018.10.002
topic Ganglia, spinal
Pain
Review
url http://www.cjcnn.org/index.php/cjcnn/article/view/1846
work_keys_str_mv AT jingzhiliu progressofdorsalrootgangliainmechanismofpain
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