Progress of dorsal root ganglia in mechanism of pain
Dorsal root ganglia (DRG) neurons are the primary afferent neurons of algaesthesis of trunk and extremities. DRG transmits and accommodates sensations and accepts and conveys nociception, so it plays an important role in the mechanism of pain. DRG is accessible to clinical interventions for the cont...
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Tianjin Huanhu Hospital
2018-10-01
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doaj-a5ccc5b74c6647f288f808a84156114a2020-11-25T02:42:01ZengTianjin Huanhu HospitalChinese Journal of Contemporary Neurology and Neurosurgery1672-67312018-10-01181070570810.3969/j.issn.1672-6731.2018.10.0021801Progress of dorsal root ganglia in mechanism of painJing-zhi LIU0Pain Management Center, the Second Hospital of Tianjin Medical University, Tianjin 300211, ChinaDorsal root ganglia (DRG) neurons are the primary afferent neurons of algaesthesis of trunk and extremities. DRG transmits and accommodates sensations and accepts and conveys nociception, so it plays an important role in the mechanism of pain. DRG is accessible to clinical interventions for the control of intractable pain and is a target for neuromodulation therapy. This review focuses on sodium ion channels in DRG, glial cells and inflammatory reaction which are mainly involved in the mechanism of pain. DOI: 10.3969/j.issn.1672-6731.2018.10.002http://www.cjcnn.org/index.php/cjcnn/article/view/1846Ganglia, spinalPainReview |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jing-zhi LIU |
spellingShingle |
Jing-zhi LIU Progress of dorsal root ganglia in mechanism of pain Chinese Journal of Contemporary Neurology and Neurosurgery Ganglia, spinal Pain Review |
author_facet |
Jing-zhi LIU |
author_sort |
Jing-zhi LIU |
title |
Progress of dorsal root ganglia in mechanism of pain |
title_short |
Progress of dorsal root ganglia in mechanism of pain |
title_full |
Progress of dorsal root ganglia in mechanism of pain |
title_fullStr |
Progress of dorsal root ganglia in mechanism of pain |
title_full_unstemmed |
Progress of dorsal root ganglia in mechanism of pain |
title_sort |
progress of dorsal root ganglia in mechanism of pain |
publisher |
Tianjin Huanhu Hospital |
series |
Chinese Journal of Contemporary Neurology and Neurosurgery |
issn |
1672-6731 |
publishDate |
2018-10-01 |
description |
Dorsal root ganglia (DRG) neurons are the primary afferent neurons of algaesthesis of trunk and extremities. DRG transmits and accommodates sensations and accepts and conveys nociception, so it plays an important role in the mechanism of pain. DRG is accessible to clinical interventions for the control of intractable pain and is a target for neuromodulation therapy. This review focuses on sodium ion channels in DRG, glial cells and inflammatory reaction which are mainly involved in the mechanism of pain.
DOI: 10.3969/j.issn.1672-6731.2018.10.002 |
topic |
Ganglia, spinal Pain Review |
url |
http://www.cjcnn.org/index.php/cjcnn/article/view/1846 |
work_keys_str_mv |
AT jingzhiliu progressofdorsalrootgangliainmechanismofpain |
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1724775845793366016 |