ADAR1-mediated RNA-editing of 3′UTRs in breast cancer

ADAR1-mediated RNA-editing of 3′UTRs in breast cancer

Abstract Background Whole transcriptome RNA variant analyses have shown that adenosine deaminases acting on RNA (ADAR) enzymes modify a large proportion of cellular RNAs, contributing to transcriptome diversity and cancer evolution. Despite the advances in the understanding of ADAR function in breas...

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Bibliographic Details
Main Authors: Eduardo A. Sagredo, Alejandro Blanco, Alfredo I. Sagredo, Paola Pérez, Gonzalo Sepúlveda-Hermosilla, Fernanda Morales, Bettina Müller, Ricardo Verdugo, Katherine Marcelain, Olivier Harismendy, Ricardo Armisén
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Biological Research
Subjects:
Breast cancer
ADAR1
3′UTR
Editing
Online Access:http://link.springer.com/article/10.1186/s40659-018-0185-4

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