Ex Vivo Akt/HO-1 Gene Therapy to Human Endothelial Progenitor Cells Enhances Myocardial Infarction Recovery

The aim of this study was to evaluate the overexpression of genes central to cell survival and angiogenesis to enhance the function of human late outgrowth endothelial progenitor cells (EPCs) and their utility for infarct recovery. Ischemic myocardial injury creates a hostile microenvironment, which...

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Bibliographic Details
Main Authors: Keith R. Brunt, Jun Wu, Zhilin Chen, Daniel Poeckel, Ryan A. Dercho, Luis G. Melo, Colin D. Funk, Christopher A. Ward, Ren-Ke Li
Format: Article
Language:English
Published: SAGE Publishing 2012-07-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368912X653002