Prediction of Protein Hotspots from Whole Protein Sequences by a Random Projection Ensemble System
Hotspot residues are important in the determination of protein-protein interactions, and they always perform specific functions in biological processes. The determination of hotspot residues is by the commonly-used method of alanine scanning mutagenesis experiments, which is always costly and time c...
Main Authors: | Jinjian Jiang, Nian Wang, Peng Chen, Chunhou Zheng, Bing Wang |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2017-07-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/18/7/1543 |
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