Effects of insulin therapy on myocardial lipid content and cardiac geometry in patients with type-2 diabetes mellitus.

AIMS/HYPOTHESIS: Recent evidence suggests a link between myocardial steatosis and diabetic cardiomyopathy. Insulin, as a lipogenic and growth-promoting hormone, might stimulate intramyocardial lipid (MYCL) deposition and hypertrophy. Therefore, the aim of the present study was to investigate the sho...

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Main Authors: Drazenka Jankovic, Yvonne Winhofer, Miriam Promintzer-Schifferl, Evelyne Wohlschläger-Krenn, Christian Heinz Anderwald, Peter Wolf, Thomas Scherer, Gert Reiter, Siegfried Trattnig, Anton Luger, Michael Krebs, Martin Krssak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3513303?pdf=render