Cavin-3 dictates the balance between ERK and Akt signaling

Cavin-3 dictates the balance between ERK and Akt signaling

Cavin-3 is a tumor suppressor protein of unknown function. Using both in vivo and in vitro approaches, we show that cavin-3 dictates the balance between ERK and Akt signaling. Loss of cavin-3 increases Akt signaling at the expense of ERK, while gain of cavin-3 increases ERK signaling at the expense...

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Bibliographic Details
Main Authors: Victor J Hernandez, Jian Weng, Peter Ly, Shanica Pompey, Hongyun Dong, Lopa Mishra, Margaret Schwarz, Richard GW Anderson, Peter Michaely
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2013-09-01
Series:eLife
Subjects:
Cavin-3
hSRBC
PRKCDBP
ERK
Akt
aerobic glycolysis
Online Access:https://elifesciences.org/articles/00905

Internet

https://elifesciences.org/articles/00905

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