| Summary: | Matthew F Hudson Greenville Hospital System, Greenville, SC, USA Abstract: This discussion defines various research approaches undertaken in health care or health promotion settings, notably basic science research, translational research, comparative effectiveness research (CER), implementation sciences, and quality improvement. This discussion particularly clarifies the relationship between translational research implementation sciences, comparative effectiveness research (CER), and quality improvement; this discussion further notes how these particular efforts are included in the Health Service Research. The discussion may: (1) introduce novice researchers, practitioners and administrators to various research approaches, (2) establish shared language that enhances comprehension of research strategies sharing similar attributes, and (3) clarify future research direction and resource allocation for health researchers, administrators, and practitioners. Keywords: basic science, translational research, comparative effectiveness research, implementation sciences, quality improvement, accountable care
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