Beyond the CNS: The many peripheral roles of APOE

Apolipoprotein E (APOE) is a multifunctional protein synthesized and secreted by multiple mammalian tissues. Although hepatocytes contribute about 75% of the peripheral pool, APOE can also be expressed in adipose tissue, the kidney, and the adrenal glands, among other tissues. High levels of APOE pr...

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Bibliographic Details
Main Authors: Ana B. Martínez-Martínez, Elena Torres-Perez, Nicholas Devanney, Raquel Del Moral, Lance A. Johnson, Jose M. Arbones-Mainar
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S096999612030084X