Convection-Enhanced Delivery: Connection to and Impact of Interstitial Fluid Flow

Convection-enhanced delivery (CED) is a method used to increase transport of therapeutics in and around brain tumors. CED works through locally applying a pressure differential to drive fluid flow throughout the tumor, such that convective forces dominate over diffusive transport. This allows therap...

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Bibliographic Details
Main Authors: Caleb A. Stine, Jennifer M. Munson
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Oncology
Subjects:
CED
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00966/full