Primary hyperparathyroidism in a child: The musculoskeletal manifestations of a late presenting rare endocrinopathy

Primary hyperparathyroidism (PHPT) is rare in children and adolescents, but has greater morbidity in this age group. Most of these patients show predominantly skeletal pathology and to a lesser extent renal involvement. Osteopenia, osteoporosis and subperiosteal resorption are frequently encountered...

Full description

Bibliographic Details
Main Authors: Tamer Ahmed EL-Sobky, Khaled A. Ahmad, Shady Samir, Dalia M.E. EL Mikkawy
Format: Article
Language:English
Published: SpringerOpen 2016-12-01
Series:The Egyptian Journal of Radiology and Nuclear Medicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0378603X16301681
id doaj-a58b2732e91a44c8b51e159d0f906a6b
record_format Article
spelling doaj-a58b2732e91a44c8b51e159d0f906a6b2020-11-25T02:16:17ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine0378-603X2016-12-014741613161610.1016/j.ejrnm.2016.09.002Primary hyperparathyroidism in a child: The musculoskeletal manifestations of a late presenting rare endocrinopathyTamer Ahmed EL-Sobky0Khaled A. Ahmad1Shady Samir2Dalia M.E. EL Mikkawy3Department of Orthopedic Surgery, Division of Paediatric Orthopaedics, Faculty of Medicine, Ain-Shams University, 38 Abbasia, Cairo, EgyptDepartment of Radiology, Division of Paediatric Radiology, Faculty of Medicine, Ain-Shams University, 38 Abbasia, Cairo, EgyptDepartment of Orthopedic Surgery, Division of Paediatric Orthopaedics, Faculty of Medicine, Ain-Shams University, 38 Abbasia, Cairo, EgyptDepartment of Rheumatology and Rehabilitation, Division of Paediatric Rheumatology and Rehabilitation, Faculty of Medicine, Ain-Shams University, 38 Abbasia, Cairo, EgyptPrimary hyperparathyroidism (PHPT) is rare in children and adolescents, but has greater morbidity in this age group. Most of these patients show predominantly skeletal pathology and to a lesser extent renal involvement. Osteopenia, osteoporosis and subperiosteal resorption are frequently encountered radiographic skeletal signs. This study describes the orthopedic manifestations of PHPT in a child. PHPT in this child exhibited a late presentation with significant clinical morbidity and extensive radiographic manifestations. The characteristic radiographic pattern of PHPT in childhood is an important contributor to the diagnosis. The radioclinical and biochemical correlations augment diagnostic accuracy and delineate extent of skeletal pathology.http://www.sciencedirect.com/science/article/pii/S0378603X16301681Pathological fracturesOrthopedicPediatric hypercalcemiaMetabolic endocrinal bone diseaseSkeletal imagingPediatric osteoporosis
collection DOAJ
language English
format Article
sources DOAJ
author Tamer Ahmed EL-Sobky
Khaled A. Ahmad
Shady Samir
Dalia M.E. EL Mikkawy
spellingShingle Tamer Ahmed EL-Sobky
Khaled A. Ahmad
Shady Samir
Dalia M.E. EL Mikkawy
Primary hyperparathyroidism in a child: The musculoskeletal manifestations of a late presenting rare endocrinopathy
The Egyptian Journal of Radiology and Nuclear Medicine
Pathological fractures
Orthopedic
Pediatric hypercalcemia
Metabolic endocrinal bone disease
Skeletal imaging
Pediatric osteoporosis
author_facet Tamer Ahmed EL-Sobky
Khaled A. Ahmad
Shady Samir
Dalia M.E. EL Mikkawy
author_sort Tamer Ahmed EL-Sobky
title Primary hyperparathyroidism in a child: The musculoskeletal manifestations of a late presenting rare endocrinopathy
title_short Primary hyperparathyroidism in a child: The musculoskeletal manifestations of a late presenting rare endocrinopathy
title_full Primary hyperparathyroidism in a child: The musculoskeletal manifestations of a late presenting rare endocrinopathy
title_fullStr Primary hyperparathyroidism in a child: The musculoskeletal manifestations of a late presenting rare endocrinopathy
title_full_unstemmed Primary hyperparathyroidism in a child: The musculoskeletal manifestations of a late presenting rare endocrinopathy
title_sort primary hyperparathyroidism in a child: the musculoskeletal manifestations of a late presenting rare endocrinopathy
publisher SpringerOpen
series The Egyptian Journal of Radiology and Nuclear Medicine
issn 0378-603X
publishDate 2016-12-01
description Primary hyperparathyroidism (PHPT) is rare in children and adolescents, but has greater morbidity in this age group. Most of these patients show predominantly skeletal pathology and to a lesser extent renal involvement. Osteopenia, osteoporosis and subperiosteal resorption are frequently encountered radiographic skeletal signs. This study describes the orthopedic manifestations of PHPT in a child. PHPT in this child exhibited a late presentation with significant clinical morbidity and extensive radiographic manifestations. The characteristic radiographic pattern of PHPT in childhood is an important contributor to the diagnosis. The radioclinical and biochemical correlations augment diagnostic accuracy and delineate extent of skeletal pathology.
topic Pathological fractures
Orthopedic
Pediatric hypercalcemia
Metabolic endocrinal bone disease
Skeletal imaging
Pediatric osteoporosis
url http://www.sciencedirect.com/science/article/pii/S0378603X16301681
work_keys_str_mv AT tamerahmedelsobky primaryhyperparathyroidisminachildthemusculoskeletalmanifestationsofalatepresentingrareendocrinopathy
AT khaledaahmad primaryhyperparathyroidisminachildthemusculoskeletalmanifestationsofalatepresentingrareendocrinopathy
AT shadysamir primaryhyperparathyroidisminachildthemusculoskeletalmanifestationsofalatepresentingrareendocrinopathy
AT daliameelmikkawy primaryhyperparathyroidisminachildthemusculoskeletalmanifestationsofalatepresentingrareendocrinopathy
_version_ 1724891406774829056