Primary hyperparathyroidism in a child: The musculoskeletal manifestations of a late presenting rare endocrinopathy
Primary hyperparathyroidism (PHPT) is rare in children and adolescents, but has greater morbidity in this age group. Most of these patients show predominantly skeletal pathology and to a lesser extent renal involvement. Osteopenia, osteoporosis and subperiosteal resorption are frequently encountered...
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doaj-a58b2732e91a44c8b51e159d0f906a6b2020-11-25T02:16:17ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine0378-603X2016-12-014741613161610.1016/j.ejrnm.2016.09.002Primary hyperparathyroidism in a child: The musculoskeletal manifestations of a late presenting rare endocrinopathyTamer Ahmed EL-Sobky0Khaled A. Ahmad1Shady Samir2Dalia M.E. EL Mikkawy3Department of Orthopedic Surgery, Division of Paediatric Orthopaedics, Faculty of Medicine, Ain-Shams University, 38 Abbasia, Cairo, EgyptDepartment of Radiology, Division of Paediatric Radiology, Faculty of Medicine, Ain-Shams University, 38 Abbasia, Cairo, EgyptDepartment of Orthopedic Surgery, Division of Paediatric Orthopaedics, Faculty of Medicine, Ain-Shams University, 38 Abbasia, Cairo, EgyptDepartment of Rheumatology and Rehabilitation, Division of Paediatric Rheumatology and Rehabilitation, Faculty of Medicine, Ain-Shams University, 38 Abbasia, Cairo, EgyptPrimary hyperparathyroidism (PHPT) is rare in children and adolescents, but has greater morbidity in this age group. Most of these patients show predominantly skeletal pathology and to a lesser extent renal involvement. Osteopenia, osteoporosis and subperiosteal resorption are frequently encountered radiographic skeletal signs. This study describes the orthopedic manifestations of PHPT in a child. PHPT in this child exhibited a late presentation with significant clinical morbidity and extensive radiographic manifestations. The characteristic radiographic pattern of PHPT in childhood is an important contributor to the diagnosis. The radioclinical and biochemical correlations augment diagnostic accuracy and delineate extent of skeletal pathology.http://www.sciencedirect.com/science/article/pii/S0378603X16301681Pathological fracturesOrthopedicPediatric hypercalcemiaMetabolic endocrinal bone diseaseSkeletal imagingPediatric osteoporosis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Tamer Ahmed EL-Sobky Khaled A. Ahmad Shady Samir Dalia M.E. EL Mikkawy |
spellingShingle |
Tamer Ahmed EL-Sobky Khaled A. Ahmad Shady Samir Dalia M.E. EL Mikkawy Primary hyperparathyroidism in a child: The musculoskeletal manifestations of a late presenting rare endocrinopathy The Egyptian Journal of Radiology and Nuclear Medicine Pathological fractures Orthopedic Pediatric hypercalcemia Metabolic endocrinal bone disease Skeletal imaging Pediatric osteoporosis |
author_facet |
Tamer Ahmed EL-Sobky Khaled A. Ahmad Shady Samir Dalia M.E. EL Mikkawy |
author_sort |
Tamer Ahmed EL-Sobky |
title |
Primary hyperparathyroidism in a child: The musculoskeletal manifestations of a late presenting rare endocrinopathy |
title_short |
Primary hyperparathyroidism in a child: The musculoskeletal manifestations of a late presenting rare endocrinopathy |
title_full |
Primary hyperparathyroidism in a child: The musculoskeletal manifestations of a late presenting rare endocrinopathy |
title_fullStr |
Primary hyperparathyroidism in a child: The musculoskeletal manifestations of a late presenting rare endocrinopathy |
title_full_unstemmed |
Primary hyperparathyroidism in a child: The musculoskeletal manifestations of a late presenting rare endocrinopathy |
title_sort |
primary hyperparathyroidism in a child: the musculoskeletal manifestations of a late presenting rare endocrinopathy |
publisher |
SpringerOpen |
series |
The Egyptian Journal of Radiology and Nuclear Medicine |
issn |
0378-603X |
publishDate |
2016-12-01 |
description |
Primary hyperparathyroidism (PHPT) is rare in children and adolescents, but has greater morbidity in this age group. Most of these patients show predominantly skeletal pathology and to a lesser extent renal involvement. Osteopenia, osteoporosis and subperiosteal resorption are frequently encountered radiographic skeletal signs. This study describes the orthopedic manifestations of PHPT in a child. PHPT in this child exhibited a late presentation with significant clinical morbidity and extensive radiographic manifestations. The characteristic radiographic pattern of PHPT in childhood is an important contributor to the diagnosis. The radioclinical and biochemical correlations augment diagnostic accuracy and delineate extent of skeletal pathology. |
topic |
Pathological fractures Orthopedic Pediatric hypercalcemia Metabolic endocrinal bone disease Skeletal imaging Pediatric osteoporosis |
url |
http://www.sciencedirect.com/science/article/pii/S0378603X16301681 |
work_keys_str_mv |
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