Analysis of GzmbCre as a Model System for Gene Deletion in the Natural Killer Cell Lineage.

The analysis of gene function in mature and activated natural killer cells has been hampered by the lack of model systems for Cre-mediated recombination in these cells. Here we have investigated the utility of GzmbCre for recombination of loxp sequences in these cells predicated on the observation t...

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Bibliographic Details
Main Authors: Yiying Xu, Cesar Evaristo, Maria-Luisa Alegre, Sandeep Gurbuxani, Barbara L Kee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4414598?pdf=render