ID1 promotes hepatocellular carcinoma proliferation and confers chemoresistance to oxaliplatin by activating pentose phosphate pathway

ID1 promotes hepatocellular carcinoma proliferation and confers chemoresistance to oxaliplatin by activating pentose phosphate pathway

Abstract Background Drug resistance is one of the major concerns in the treatment of hepatocellular carcinoma (HCC). The aim of the present study was to determine whether aberrant high expression of the inhibitor of differentiation 1(ID1) confers oxaliplatin-resistance to HCC by activating the pento...

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Bibliographic Details
Main Authors:	Xin Yin, Bei Tang, Jing-Huan Li, Yan Wang, Lan Zhang, Xiao-Ying Xie, Bo-Heng Zhang, Shuang-Jian Qiu, Wei-Zhong Wu, Zheng-Gang Ren
Format:	Article
Language:	English
Published:	BMC 2017-11-01
Series:	Journal of Experimental & Clinical Cancer Research
Subjects:	Hepatocellular carcinoma ID1 (inhibitor of differentiation and DNA binding-1) Pentose phosphate pathway Chemoresistance
Online Access:	http://link.springer.com/article/10.1186/s13046-017-0637-7

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