Artificially introduced aneuploid chromosomes assume a conserved position in colon cancer cells.

Artificially introduced aneuploid chromosomes assume a conserved position in colon cancer cells.

BACKGROUND:Chromosomal aneuploidy is a defining feature of carcinomas. For instance, in colon cancer, an additional copy of Chromosome 7 is not only observed in early pre-malignant polyps, but is faithfully maintained throughout progression to metastasis. These copy number changes show a positive co...

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Bibliographic Details
Main Authors: Kundan Sengupta, Madhvi B Upender, Linda Barenboim-Stapleton, Quang Tri Nguyen, Stephen M Wincovitch, Susan H Garfield, Michael J Difilippantonio, Thomas Ried
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1805818?pdf=render

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