Recent advances in understanding Kaposi’s sarcoma-associated herpesvirus [version 1; referees: 2 approved]

Recent advances in understanding Kaposi’s sarcoma-associated herpesvirus [version 1; referees: 2 approved]

Kaposi’s sarcoma (KS)-associated herpesvirus (KSHV) is an oncogenic human herpesvirus. KSHV is associated with three cancers in the human population: KS, primary effusion lymphoma (PEL), and multicentric Castleman’s disease (MCD). KS is the leading cause of cancer in HIV-infected individuals. In thi...

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Bibliographic Details
Main Authors: Nathan J. Dissinger, Blossom Damania
Format: Article
Language:English
Published: F1000 Research Ltd 2016-04-01
Series:F1000Research
Subjects:
Antimicrobials & Drug Resistance
Cell Signaling
Cellular Death & Stress Responses
Cellular Microbiology & Pathogenesis
Control of Gene Expression
Medical Microbiology
Nuclear Structure & Function
Virology
Online Access:http://f1000research.com/articles/5-740/v1
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spelling doaj-a569b1900e364947856dc390a83918ba2020-11-25T02:53:50ZengF1000 Research LtdF1000Research2046-14022016-04-01510.12688/f1000research.7612.18198Recent advances in understanding Kaposi’s sarcoma-associated herpesvirus [version 1; referees: 2 approved]Nathan J. Dissinger0Blossom Damania1Lineberger Comprehensive Cancer Center and Department of Microbiology & Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USALineberger Comprehensive Cancer Center and Department of Microbiology & Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USAKaposi’s sarcoma (KS)-associated herpesvirus (KSHV) is an oncogenic human herpesvirus. KSHV is associated with three cancers in the human population: KS, primary effusion lymphoma (PEL), and multicentric Castleman’s disease (MCD). KS is the leading cause of cancer in HIV-infected individuals. In this review, we discuss the most recent discoveries behind the mechanisms of KSHV latency maintenance and lytic replication. We also review current therapies for KSHV-associated cancers.http://f1000research.com/articles/5-740/v1Antimicrobials & Drug ResistanceCell SignalingCellular Death & Stress ResponsesCellular Microbiology & PathogenesisControl of Gene ExpressionMedical MicrobiologyNuclear Structure & FunctionVirology
collection DOAJ
language English
format Article
sources DOAJ
author Nathan J. Dissinger
Blossom Damania
spellingShingle Nathan J. Dissinger
Blossom Damania
Recent advances in understanding Kaposi’s sarcoma-associated herpesvirus [version 1; referees: 2 approved]
F1000Research
Antimicrobials & Drug Resistance
Cell Signaling
Cellular Death & Stress Responses
Cellular Microbiology & Pathogenesis
Control of Gene Expression
Medical Microbiology
Nuclear Structure & Function
Virology
author_facet Nathan J. Dissinger
Blossom Damania
author_sort Nathan J. Dissinger
title Recent advances in understanding Kaposi’s sarcoma-associated herpesvirus [version 1; referees: 2 approved]
title_short Recent advances in understanding Kaposi’s sarcoma-associated herpesvirus [version 1; referees: 2 approved]
title_full Recent advances in understanding Kaposi’s sarcoma-associated herpesvirus [version 1; referees: 2 approved]
title_fullStr Recent advances in understanding Kaposi’s sarcoma-associated herpesvirus [version 1; referees: 2 approved]
title_full_unstemmed Recent advances in understanding Kaposi’s sarcoma-associated herpesvirus [version 1; referees: 2 approved]
title_sort recent advances in understanding kaposi’s sarcoma-associated herpesvirus [version 1; referees: 2 approved]
publisher F1000 Research Ltd
series F1000Research
issn 2046-1402
publishDate 2016-04-01
description Kaposi’s sarcoma (KS)-associated herpesvirus (KSHV) is an oncogenic human herpesvirus. KSHV is associated with three cancers in the human population: KS, primary effusion lymphoma (PEL), and multicentric Castleman’s disease (MCD). KS is the leading cause of cancer in HIV-infected individuals. In this review, we discuss the most recent discoveries behind the mechanisms of KSHV latency maintenance and lytic replication. We also review current therapies for KSHV-associated cancers.
topic Antimicrobials & Drug Resistance
Cell Signaling
Cellular Death & Stress Responses
Cellular Microbiology & Pathogenesis
Control of Gene Expression
Medical Microbiology
Nuclear Structure & Function
Virology
url http://f1000research.com/articles/5-740/v1
work_keys_str_mv AT nathanjdissinger recentadvancesinunderstandingkaposissarcomaassociatedherpesvirusversion1referees2approved
AT blossomdamania recentadvancesinunderstandingkaposissarcomaassociatedherpesvirusversion1referees2approved
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