Advances in Predictions of Oral Bioavailability of Candidate Drugs in Man with New Machine Learning Methodology

Oral bioavailability (F) is an essential determinant for the systemic exposure and dosing regimens of drug candidates. F is determined by numerous processes, and computational predictions of human estimates have so far shown limited results. We describe a new methodology where F in humans is predict...

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Bibliographic Details
Main Authors: Urban Fagerholm, Sven Hellberg, Ola Spjuth
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/9/2572

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