Chemokine Receptor 5 Antagonism Causes Reduction in Joint Inflammation in a Collagen-Induced Arthritis Mouse Model

Chemokine Receptor 5 Antagonism Causes Reduction in Joint Inflammation in a Collagen-Induced Arthritis Mouse Model

Rheumatoid arthritis (RA) is a chronic inflammatory disease mainly affecting the synovial joints. A highly potent antagonist of C-C chemokine receptor 5 (CCR5), maraviroc (MVC), plays an essential role in treating several infectious diseases but has not yet been evaluated for its potential effects o...

Full description

Bibliographic Details
Main Authors: Mushtaq A. Ansari, Ahmed Nadeem, Saleh A. Bakheet, Sabry M. Attia, Mudassar Shahid, Faris S. Alyousef, Mohammed A. Alswailem, Mohammed Alqinyah, Sheikh F. Ahmad
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Molecules
Subjects:
maraviroc
CCR5 antagonist
inflammation
collagen-induced arthritis
CD8 cells
Online Access:https://www.mdpi.com/1420-3049/26/7/1839

Similar Items

Similar Items