Cross-Protective Immune Responses Induced by Sequential Influenza Virus Infection and by Sequential Vaccination With Inactivated Influenza Vaccines

Cross-Protective Immune Responses Induced by Sequential Influenza Virus Infection and by Sequential Vaccination With Inactivated Influenza Vaccines

Sequential infection with antigenically distinct influenza viruses induces cross-protective immune responses against heterologous virus strains in animal models. Here we investigated whether sequential immunization with antigenically distinct influenza vaccines can also provide cross-protection. To...

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Bibliographic Details
Main Authors: Wei Dong, Yoshita Bhide, Federica Sicca, Tjarko Meijerhof, Kate Guilfoyle, Othmar G. Engelhardt, Louis Boon, Cornelis A. M. de Haan, George Carnell, Nigel Temperton, Jacqueline de Vries-Idema, David Kelvin, Anke Huckriede
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
sequential vaccination
cross-protection
antigenically distinct influenza virus strains
immune mechanism
non-neutralizing antibody
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02312/full

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