Allogeneic Mesenchymal Precursor Cells (MPC) in Diabetic Nephropathy: A Randomized, Placebo-controlled, Dose Escalation Study

Allogeneic Mesenchymal Precursor Cells (MPC) in Diabetic Nephropathy: A Randomized, Placebo-controlled, Dose Escalation Study

Background: Diabetic nephropathy is the most common cause of end stage renal failure. We assessed the safety, tolerability, and explored therapeutic effects of adult allogeneic bone-marrow derived mesenchymal precursor cells (MPC) in patients with moderate to severe diabetic nephropathy. Methods: Mu...

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Bibliographic Details
Main Authors: David K. Packham, MD, Ian R. Fraser, MD, Peter G. Kerr, MBBS, Karen R. Segal, PhD
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:EBioMedicine
Subjects:
Mesenchymal precursor cells
Diabetic nephropathy
Stem cell
Inflammation
Glomerular filtration rate
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396416304182

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http://www.sciencedirect.com/science/article/pii/S2352396416304182

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