Enhancement of Radiotherapeutic Efficacy by Paclitaxel-Loaded pH-Sensitive Block Copolymer Micelles

Radiotherapy (RT) is a major modality for cancer treatment, but its efficacy is often compromised by the resistance caused by tumor-specific microenvironment including acidosis and hypoxia. For an effective RT, concurrent administration of radiosensitizer with RT has been emphasized. However, most a...

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Bibliographic Details
Main Authors: Joohee Jung, Min Sang Kim, Sung-Jin Park, Hye Kyung Chung, Jinhyang Choi, Jaesook Park, Dong-Hoon Jin, Si Yeol Song, Heon Joo Park, Doo Sung Lee, Seong-Yun Jeong, Eun Kyung Choi
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Nanomaterials
Online Access:http://dx.doi.org/10.1155/2012/867036