Whole-genome sequencing in bacteriology: state of the art

Michael J DarkDepartment of Infectious Diseases and Pathology and Emerging Pathogens Institute, University of Florida, Gainesville, FL, USAAbstract: Over the last ten years, genome sequencing capabilities have expanded exponentially. There have been tremendous advances in sequencing technology, DNA...

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Main Author: Dark MJ
Format: Article
Language:English
Published: Dove Medical Press 2013-10-01
Series:Infection and Drug Resistance
Online Access:http://www.dovepress.com/nbspwhole-genome-sequencing-in-bacteriology-state-of-the-art-a14608
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spelling doaj-a4edbbed5aed4220802476bb17d268352020-11-24T23:08:59ZengDove Medical PressInfection and Drug Resistance1178-69732013-10-012013default115123Whole-genome sequencing in bacteriology: state of the artDark MJMichael J DarkDepartment of Infectious Diseases and Pathology and Emerging Pathogens Institute, University of Florida, Gainesville, FL, USAAbstract: Over the last ten years, genome sequencing capabilities have expanded exponentially. There have been tremendous advances in sequencing technology, DNA sample preparation, genome assembly, and data analysis. This has led to advances in a number of facets of bacterial genomics, including metagenomics, clinical medicine, bacterial archaeology, and bacterial evolution. This review examines the strengths and weaknesses of techniques in bacterial genome sequencing, upcoming technologies, and assembly techniques, as well as highlighting recent studies that highlight new applications for bacterial genomics.Keywords: bacterial genome sequencing assembly reviewhttp://www.dovepress.com/nbspwhole-genome-sequencing-in-bacteriology-state-of-the-art-a14608
collection DOAJ
language English
format Article
sources DOAJ
author Dark MJ
spellingShingle Dark MJ
Whole-genome sequencing in bacteriology: state of the art
Infection and Drug Resistance
author_facet Dark MJ
author_sort Dark MJ
title Whole-genome sequencing in bacteriology: state of the art
title_short Whole-genome sequencing in bacteriology: state of the art
title_full Whole-genome sequencing in bacteriology: state of the art
title_fullStr Whole-genome sequencing in bacteriology: state of the art
title_full_unstemmed Whole-genome sequencing in bacteriology: state of the art
title_sort whole-genome sequencing in bacteriology: state of the art
publisher Dove Medical Press
series Infection and Drug Resistance
issn 1178-6973
publishDate 2013-10-01
description Michael J DarkDepartment of Infectious Diseases and Pathology and Emerging Pathogens Institute, University of Florida, Gainesville, FL, USAAbstract: Over the last ten years, genome sequencing capabilities have expanded exponentially. There have been tremendous advances in sequencing technology, DNA sample preparation, genome assembly, and data analysis. This has led to advances in a number of facets of bacterial genomics, including metagenomics, clinical medicine, bacterial archaeology, and bacterial evolution. This review examines the strengths and weaknesses of techniques in bacterial genome sequencing, upcoming technologies, and assembly techniques, as well as highlighting recent studies that highlight new applications for bacterial genomics.Keywords: bacterial genome sequencing assembly review
url http://www.dovepress.com/nbspwhole-genome-sequencing-in-bacteriology-state-of-the-art-a14608
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