S1P-S1PR1 Signaling: the “Sphinx” in Osteoimmunology

The fundamental interaction between the immune and skeletal systems, termed as osteoimmunology, has been demonstrated to play indispensable roles in the maintenance of balance between bone resorption and formation. The pleiotropic sphingolipid metabolite, sphingosine 1-phosphate (S1P), together with...

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Bibliographic Details
Main Authors: Lan Xiao, Yinghong Zhou, Thor Friis, Kenneth Beagley, Yin Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01409/full