Tardive dystonia improved with discontinuation of trazodone in an elderly schizophrenia patient: a case report

Abstract Background Tardive dystonia associated with antidepressant use is rare and often under-recognized. We had an experience with trazodone, which is used for delirium and insomnia prescribed in general hospital, inducing tardive dystonia. Case presentation A 61-year-old Japanese woman had been...

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Bibliographic Details
Main Authors: Yoshinori Kadota, Hikaru Hori, Michiko Takayama, Chikako Okabe, Naotoshi Ohara
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Annals of General Psychiatry
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12991-020-00273-8
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Summary:Abstract Background Tardive dystonia associated with antidepressant use is rare and often under-recognized. We had an experience with trazodone, which is used for delirium and insomnia prescribed in general hospital, inducing tardive dystonia. Case presentation A 61-year-old Japanese woman had been treated for schizophrenia. She was moved to general hospital because of consciousness disturbance. She was prescribed trazodone (25 mg/day) for delirium and insomnia. After she was discharged, she returned to the psychiatric hospital with tardive dystonia. Her dystonia symptoms improved with 3 days of discontinuing trazodone. Conclusion In the present case, long-term use of trazodone induced tardive dystonia. Discontinuing trazodone rapidly improved tardive dystonia.
ISSN:1744-859X