Combinatorial Libraries on Rigid Scaffolds: Solid Phase Synthesis of Variably Substituted Pyrazoles and Isoxazoles

The synthesis of combinatorial compound libraries has become a powerful lead finding tool in modern drug discovery. The ability to synthesize rapidly, in high yield, new chemical entities with low molecular weight on a solid support has a recognized strategic relevance (“small molecule librarie...

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Bibliographic Details
Main Authors: Eduard R. Felder, Andreas L. Marzinzik
Format: Article
Language:English
Published: MDPI AG 1997-01-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/2/1/17/