Clock-dependent temporal regulation of IL-33/ST2-mediated mast cell response

Clock-dependent temporal regulation of IL-33/ST2-mediated mast cell response

Background: Interleukin-33 (IL-33) is an alarmin cytokine that binds to the interleukin 1 receptor-like 1 protein ST2. Clock is a key circadian gene that is essential for endogenous clockworks in mammals. This study investigated whether Clock temporally regulated IL-33-mediated responses in mast cel...

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Bibliographic Details
Main Authors: Takahiro Kawauchi, Kayoko Ishimaru, Yuki Nakamura, Nobuhiro Nakano, Mutsuko Hara, Hideoki Ogawa, Ko Okumura, Shigenobu Shibata, Atsuhito Nakao
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Allergology International
Subjects:
CLOCK
Cytokine
IL-33
Mast cells
ST2
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893017300084

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