The Natural History of Globus Pharyngeus

Globus pharyngeus is a common disorder and accounts for 5% of all ENT referrals. Objectives. To evaluate the role of barium swallow and endoscopy in these patients, to ascertain the incidence, if any, of aerodigestive tract malignancy in this group and to assess the natural evolution of globus phary...

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Main Authors: E. C. Cashman, M. J. Donnelly
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:International Journal of Otolaryngology
Online Access:http://dx.doi.org/10.1155/2010/159630
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spelling doaj-a4bfcd0132aa4c5990af7533eb234bc02020-11-24T22:26:52ZengHindawi LimitedInternational Journal of Otolaryngology1687-92011687-921X2010-01-01201010.1155/2010/159630159630The Natural History of Globus PharyngeusE. C. Cashman0M. J. Donnelly1Dana-Farber Cancer Institute,Harvard Medical School, Longwood Avenue, Boston, MA 02115, USADepartment of Otolaryngology, Waterford Regional Hospital, Waterford, IrelandGlobus pharyngeus is a common disorder and accounts for 5% of all ENT referrals. Objectives. To evaluate the role of barium swallow and endoscopy in these patients, to ascertain the incidence, if any, of aerodigestive tract malignancy in this group and to assess the natural evolution of globus pharyngeus. Materials and Methods. Seventy-nine patients underwent barium swallow and rigid oesophagoscopy for globus pharyngeus between January 2005 and October 2008. Fifty-five patients were contacted by phone on average 5 years and 3 months after intervention and asked if their symptoms still persisted. Twenty-four patients were uncontactable or lost to followup, three patients were deceased, two of cardiac related disease and one of renal failure. Results. The majority of patients, 36 of 55 (65%), had a normal barium swallow. Forty-five of 55 (82%) of patients had normal rigid endoscopies. Thirty-one of 55 (56%) patients were at an average followup time of 5 years and 3 months. No patient developed a malignant lesion. Conclusion. Globus pharyngeus is a relatively common but benign condition of indeterminate origin. Our study demonstrates that many of these patients spontaneously improve with time.http://dx.doi.org/10.1155/2010/159630
collection DOAJ
language English
format Article
sources DOAJ
author E. C. Cashman
M. J. Donnelly
spellingShingle E. C. Cashman
M. J. Donnelly
The Natural History of Globus Pharyngeus
International Journal of Otolaryngology
author_facet E. C. Cashman
M. J. Donnelly
author_sort E. C. Cashman
title The Natural History of Globus Pharyngeus
title_short The Natural History of Globus Pharyngeus
title_full The Natural History of Globus Pharyngeus
title_fullStr The Natural History of Globus Pharyngeus
title_full_unstemmed The Natural History of Globus Pharyngeus
title_sort natural history of globus pharyngeus
publisher Hindawi Limited
series International Journal of Otolaryngology
issn 1687-9201
1687-921X
publishDate 2010-01-01
description Globus pharyngeus is a common disorder and accounts for 5% of all ENT referrals. Objectives. To evaluate the role of barium swallow and endoscopy in these patients, to ascertain the incidence, if any, of aerodigestive tract malignancy in this group and to assess the natural evolution of globus pharyngeus. Materials and Methods. Seventy-nine patients underwent barium swallow and rigid oesophagoscopy for globus pharyngeus between January 2005 and October 2008. Fifty-five patients were contacted by phone on average 5 years and 3 months after intervention and asked if their symptoms still persisted. Twenty-four patients were uncontactable or lost to followup, three patients were deceased, two of cardiac related disease and one of renal failure. Results. The majority of patients, 36 of 55 (65%), had a normal barium swallow. Forty-five of 55 (82%) of patients had normal rigid endoscopies. Thirty-one of 55 (56%) patients were at an average followup time of 5 years and 3 months. No patient developed a malignant lesion. Conclusion. Globus pharyngeus is a relatively common but benign condition of indeterminate origin. Our study demonstrates that many of these patients spontaneously improve with time.
url http://dx.doi.org/10.1155/2010/159630
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