Recombinant Expression and Characterization of α-Conotoxin LvIA in Escherichia coli

Recombinant Expression and Characterization of α-Conotoxin LvIA in Escherichia coli

α-Conotoxin LvIA is derived from Conus lividus, native to Hainan, and is the most selective inhibitor of α3β2 nicotinic acetylcholine receptors (nAChRs) known to date. In this study, an efficient approach for the production of recombinant α-Conotoxin LvIA is described. Tandem repeats of a LvIA gene...

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Bibliographic Details
Main Authors: Xiaopeng Zhu, Jianpeng Bi, Jinpeng Yu, Xiaodan Li, Yaning Zhang, Dongting Zhangsun, Sulan Luo
Format: Article
Language:English
Published: MDPI AG 2016-01-01
Series:Marine Drugs
Subjects:
α-conotoxin LvIA
recombinant expression
fusion protein
nAChRs
electrophysiology
pain assay
Online Access:http://www.mdpi.com/1660-3397/14/1/11

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