Identification problem for stochastic models with application to carcinogenesis, cancer detection and radiation biology

A general framework for solving identification problem for a broad class of deterministic and stochastic models is discussed. This methodology allows for a unified approach to studying identifiability of various stochastic models arising in biology and medicine including models of spontaneous and in...

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Bibliographic Details
Main Author: L. G. Hanin
Format: Article
Language:English
Published: Hindawi Limited 2002-01-01
Series:Discrete Dynamics in Nature and Society
Subjects:
Online Access:http://dx.doi.org/10.1080/1026022021000001454
Description
Summary:A general framework for solving identification problem for a broad class of deterministic and stochastic models is discussed. This methodology allows for a unified approach to studying identifiability of various stochastic models arising in biology and medicine including models of spontaneous and induced Carcinogenesis, tumor progression and detection, and randomized hit and target models of irradiated cell survival. A variety of known results on parameter identification for stochastic models is reviewed and several new results are presented with an emphasis on rigorous mathematical development.
ISSN:1026-0226
1607-887X