Dynamics of membrane lipid domains in neuronal cells differentiated in culture1

Dynamics of membrane lipid domains in neuronal cells differentiated in culture1

Treatment with methyl-β-cyclodextrin (MCD) induced a time- and dose-dependent efflux of cholesterol, sphingolipids, and phosphatidylcholine (PC) from cerebellar neurons differentiated in culture. With a “mild” treatment, the loss of cell lipids induced a deep reorganization of the remaining membrane...

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Bibliographic Details
Main Authors: Elena Ottico, Alessandro Prinetti, Simona Prioni, Claudia Giannotta, Luisa Basso, Vanna Chigorno, Sandro Sonnino
Format: Article
Language:English
Published: Elsevier 2003-11-01
Series:Journal of Lipid Research
Subjects:
cholesterol
sphingomyelin
ganglioside
sphingolipid-enriched membrane domain
cyclodextrin
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520336889

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