Monitoring method for transgene expression in target tissue by blood sampling

In this study, we have developed a novel method to monitor transgene expression in tissues by blood sampling. We administered plasmid DNA (pDNA) encoding non-secretory form of firefly luciferase as a reporter gene and pDNA encoding secretable Gaussia princeps luciferase as a monitor gene simultaneou...

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Bibliographic Details
Main Authors: Eriko Kinoshita, Shintaro Fumoto, Yuta Hori, Naoki Yoshikawa, Hirotaka Miyamoto, Hitoshi Sasaki, Junzo Nakamura, Takashi Tanaka, Koyo Nishida
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Biotechnology Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2215017X19305168