De Novo Glioblastoma in the Territory of a Prior Middle Cerebral Artery Infarct

We report a case of a patient who developed glioblastoma in the territory of a previous infarction. Two years after an ischemic stroke, the patient presented with a cystic, necrotic, and heterogeneously enhancing mass. Open biopsy and debulking of the mass with histological analysis revealed the mas...

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Main Authors: Teresa J. Wojtasiewicz, Andrew F. Ducruet, Sonal S. Noticewala, Peter Canoll, Guy M. McKhann
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Case Reports in Neurological Medicine
Online Access:http://dx.doi.org/10.1155/2013/356526
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spelling doaj-a4964324e07f441b996c01dfe3d15da32020-11-25T00:12:21ZengHindawi LimitedCase Reports in Neurological Medicine2090-66682090-66762013-01-01201310.1155/2013/356526356526De Novo Glioblastoma in the Territory of a Prior Middle Cerebral Artery InfarctTeresa J. Wojtasiewicz0Andrew F. Ducruet1Sonal S. Noticewala2Peter Canoll3Guy M. McKhann4Department of Neurological Surgery, College of Physicians and Surgeons, Neurological Institute of New York, Columbia University, 710 W 168th Street, New York, NY 10032, USADepartment of Neurological Surgery, College of Physicians and Surgeons, Neurological Institute of New York, Columbia University, 710 W 168th Street, New York, NY 10032, USADepartment of Pathology, Columbia University, College of Physicians and Surgeons, 1130 St. Nicholas Avenue, New York, NY 10032, USADepartment of Pathology, Columbia University, College of Physicians and Surgeons, 1130 St. Nicholas Avenue, New York, NY 10032, USADepartment of Neurological Surgery, College of Physicians and Surgeons, Neurological Institute of New York, Columbia University, 710 W 168th Street, New York, NY 10032, USAWe report a case of a patient who developed glioblastoma in the territory of a previous infarction. Two years after an ischemic stroke, the patient presented with a cystic, necrotic, and heterogeneously enhancing mass. Open biopsy and debulking of the mass with histological analysis revealed the mass to be glioblastoma. Though several cases of posttraumatic GBM have been reported, this is the first proposed case of GBM after an ischemic stroke. From this case, we suggest that the ischemic stroke, like other forms of cortical injury, may predispose to glioblastoma formation.http://dx.doi.org/10.1155/2013/356526
collection DOAJ
language English
format Article
sources DOAJ
author Teresa J. Wojtasiewicz
Andrew F. Ducruet
Sonal S. Noticewala
Peter Canoll
Guy M. McKhann
spellingShingle Teresa J. Wojtasiewicz
Andrew F. Ducruet
Sonal S. Noticewala
Peter Canoll
Guy M. McKhann
De Novo Glioblastoma in the Territory of a Prior Middle Cerebral Artery Infarct
Case Reports in Neurological Medicine
author_facet Teresa J. Wojtasiewicz
Andrew F. Ducruet
Sonal S. Noticewala
Peter Canoll
Guy M. McKhann
author_sort Teresa J. Wojtasiewicz
title De Novo Glioblastoma in the Territory of a Prior Middle Cerebral Artery Infarct
title_short De Novo Glioblastoma in the Territory of a Prior Middle Cerebral Artery Infarct
title_full De Novo Glioblastoma in the Territory of a Prior Middle Cerebral Artery Infarct
title_fullStr De Novo Glioblastoma in the Territory of a Prior Middle Cerebral Artery Infarct
title_full_unstemmed De Novo Glioblastoma in the Territory of a Prior Middle Cerebral Artery Infarct
title_sort de novo glioblastoma in the territory of a prior middle cerebral artery infarct
publisher Hindawi Limited
series Case Reports in Neurological Medicine
issn 2090-6668
2090-6676
publishDate 2013-01-01
description We report a case of a patient who developed glioblastoma in the territory of a previous infarction. Two years after an ischemic stroke, the patient presented with a cystic, necrotic, and heterogeneously enhancing mass. Open biopsy and debulking of the mass with histological analysis revealed the mass to be glioblastoma. Though several cases of posttraumatic GBM have been reported, this is the first proposed case of GBM after an ischemic stroke. From this case, we suggest that the ischemic stroke, like other forms of cortical injury, may predispose to glioblastoma formation.
url http://dx.doi.org/10.1155/2013/356526
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